Optinose Exhalation Delivery System (EDS)
Deposition is different with exhalation
The Optinose Exhalation Delivery System helps deliver medication high and deep in the nasal passages.
Deposition demonstrated through gamma scintigraphy1
![Gamma scintigraphy showing deposition with a nasal spray without exhalation and an Optinose EDS](/wp-content/themes/xhance-2018/dist/images/dpstn_wth_exhltn-2.png)
Gamma camera image after using an Optinose Exhalation Delivery System with exhalation. The image is from a healthy subject taken 2 minutes after administration with radiolabeled solution and is representative of the overall findings from 211 images and 56 subjects.
The clinical relevance of different deposition patterns has not been established.
Three of the Optinose EDS key features:
Watch the Optinose EDS in action
How EDS works
![Illustrated image of the a person using an Optinose EDS](/wp-content/themes/xhance-2018/dist/images/EDS-diagram_LEFT.gif)
![Illustrated image of the a person using an Optinose EDS](/wp-content/themes/xhance-2018/dist/images/EDS-diagram_RIGHT.gif)
- Exhalation elevates the soft palate, creating a seal that separates the nasal cavity from the oropharynx.2
- Air then enters the nostril through the sealing nosepiece, helping expand narrow nasal passages.2
- Medication entrained in the breath is deposited high and deep, flowing around anatomical structures.2
- Air then escapes out the opposite nostril.2
- Exhalation elevates the soft palate, creating a seal that separates the nasal cavity from the oropharynx.2
- Air then enters the nostril through the sealing nosepiece, helping expand narrow nasal passages.2
- Medication entrained in the breath is deposited high and deep, flowing around anatomical structures.2
- Air then escapes out the opposite nostril.2
![Image of XHANCE logo. In a questionnaire of patients in clinical trials, most patients reported that XHANCE was easy to use](/wp-content/themes/xhance-2018/dist/images/body_callout-X.png)