XHANCE resources for healthcare professionals
Mechanism of Delivery and Polyp Reduction




Peer Insights
Patient Testimonials
Paid Spokesperson
Paid Spokesperson
CONTRAINDICATIONS:
Hypersensitivity to any ingredient in XHANCE.
WARNINGS AND PRECAUTIONS:
ADVERSE REACTIONS:
The most common adverse reactions (incidence ≥ 3%) are epistaxis, nasal septal ulceration, nasopharyngitis, nasal mucosal erythema, nasal mucosal ulcerations, nasal congestion, acute sinusitis, nasal septal erythema, headache, and pharyngitis.
DRUG INTERACTIONS:
Strong cytochrome P450 3A4 inhibitors (e.g., ritonavir, ketoconazole): Use not recommended. May increase risk of systemic corticosteroid effects.
USE IN SPECIFIC POPULATIONS:
Hepatic impairment. Monitor patients for signs of increased drug exposure.
INDICATION
XHANCE is a corticosteroid indicated for the treatment of chronic rhinosinusitis with nasal polyps (CRSwNP) in patients 18 years of age or older.
Please see Full Prescribing Information pdf opensfull Prescribing Information, including Instructions for Use.