FREQUENTLY ASKED QUESTIONS ABOUT XHANCE

XHANCE is a corticosteroid indicated for the treatment of nasal polyps in patients 18 years of age or older.

If your patients have questions about XHANCE, you can refer them to the Instructions for Use and tell them to visit XHANCE.com for more information.

What is the dosage form and strength of XHANCE?

  • Each metered spray delivers 93 mcg of fluticasone propionate in 106 mg of aqueous suspension

How much spray is delivered per actuation?

  • Each metered spray delivers 93 mcg of fluticasone propionate in 106 mg of aqueous suspension through the cone-shaped nosepiece. One prescribed unit dispensed from the pharmacy provides 120 metered sprays

How long will the prescription last?

  • If dosed 1 spray per nostril BID, one prescribed unit dispensed from the pharmacy will last for 30 days. If dosed 2 sprays per nostril BID, one prescribed unit dispensed from the pharmacy will last for 15 days

What is the shelf life of XHANCE?

  • The 120 Metered Spray bottle has a shelf life of 36 months. The 28 Metered Spray bottle has a shelf life of 24 months

Is XHANCE red dye free?

  • Yes

Does XHANCE contain alcohol?

  • No

Does XHANCE have a fragrance?

  • No, the product does not have a fragrance

What is the particle size?

  • Particle size distribution is in the range of 0 to 5 microns

Does XHANCE include dyes, gluten, or lactose?

  • No
Can bacteria grow in the unit due to spray dripping down the device?

  • The suspension contains a preservative (benzalkonium chloride) to prevent microbial growth

Do patients need to sniff to get the medication into the nose?

  • Patients should not inhale (sniff) when blowing (exhaling) into the mouthpiece. They should continue to blow into the mouthpiece while pressing the vial to release the medication. The exhaled breath helps to deliver the medication high and deep into the patient’s nasal passages1,2

Should patients pinch off the other nostril while using the device?

  • Patients should never block the other nostril because the exhaled breath must pass around the back of the nasal septum and out the other side of the nose

How often do patients need to clean the device?

  • Patients do not need to clean XHANCE. If they prefer to clean the device, they should remove the cap and use a clean, dry, lint-free cloth to wipe the device after each use

What should I tell my patients about how to use to ensure best results?

  • Use XHANCE regularly twice daily and continue to use as instructed. Continued use for several months may be needed for best results
  • Read the Patient Information and the Instructions for Use prior to use

How do patients use the product?

Can other medications be put into the XHANCE device?

  • No other medications can be put into the XHANCE device. XHANCE EDS is a self-contained unit; the delivery system cannot be attached to other medications


The clinical trials for XHANCE evaluated over 1500 patients.1
View endoscopy videos taken before and after treatment with XHANCE.