Diagnosing nasal polyps

Chronic inflammation associated with nasal polyposis may be the underlying cause of nasal symptoms.1,2 Defining symptoms last at least 12 weeks and include at least two of the following3:

Icon representing symptoms of nasal congestion and obstruction from CRS with nasal polyps
Nasal congestion
or obstruction
Icon representing symptoms of facial pain/pressure from CRS with nasal polyps
Icon representing symptoms of rhinorrhea or postnasal drip from CRS with nasal polyps
Rhinorrhea or
postnasal drip
Icon representing symptoms of reduction or loss of sense of smell and taste from CRS with nasal polyps
Reduction or loss of
sense of smell and taste

Nasal polyps are common but may be difficult to visualize

Nasal polyps may be difficult to see during a routine nasal exam due to complexities of the nasal anatomy and/or widespread inflammation.2,4-7

Up to 10 million adults in the United States have nasal polyps.1,8

  • In the general population, the prevalence of nasal polyps has been reported to be up to 4%9,10
  • Histopathologic evaluation of 1,944 endoscopic sinus surgery specimens removed during an 8-year period at one center found that 65% had evidence of nasal polyp tissue11
  • In XHANCE pivotal trials, patients had moderate-to-severe congestion and evidence of nasal polyps, yet up to 86% of nasal polyps at baseline likely could not be readily visualized (did not extend below the inferior turbinate) during a routine exam with speculum12
Graphic of view of nasal anatomy using a speculum in the middle turbinate
Graphic of view of nasal anatomy using an endoscope showing a nasal polyp in the middle turbinate
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